Клетъчни линии на рак на стомаха MGC-803 и BGC-823 бяха третирани със или без водородо кислородна газова смес H 2 / O 2 (66,7%: 33,3% v / v). Пролиферацията и миграцията са оценени съответно чрез MTT и анализи за заздравяване на драскотини. Експресията на lncRNA MALAT1, miR-124-3p и EZH2 се анализира чрез количествена PCR в реално време и / или Western blot. Растежът на тумора се изчислява, като се използва ксенографтен модел на мишка.
Това проучване демонстрира ефикасността на молекулярния водород за инхибиране на растежа на рак на стомаха чрез намаляване на пролиферацията и миграцията на ракови клетки на стомаха, което е чрез понижаване на регулирането на lncRNA MALAT1 и член на семейството на поликомб EZH2 и регулиране на miR-124-3p Освен това, miR-124-3p инхибира експресията на EZH2 и реципрочно потиска експресията един на друг с lncRNA MALAT1. Тези данни показват, че Н 2 следва да бъде допълнит
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