Hydrogen-rich water help of patients treated with radiotherapy for liver tumorsScientific Research

Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors



Cancer patients undergoing radiation therapy often experience fatigue and reduced quality of life (QOL). Many of the side effects of radiation therapy are thought to be related to increased oxidative stress and inflammation due to the production of reactive oxygen species during radiation therapy. Hydrogen can be used as a therapeutic medical gas, has antioxidant properties and reduces tissue inflammation. This study examined whether hydrogen therapy in the form of hydrogen-supplemented water could improve the quality of life of patients undergoing radiation therapy.


A randomized, placebo-controlled study was conducted to evaluate the effects of drinking hydrogen-enriched water in 49 patients with malignant liver tumors undergoing radiation therapy. Prepare hydrogen-rich water (final hydrogen concentration: 0.55-0.65 mM) by placing metallic magnesium rods in drinking water.After 14 days of intervention, HRW intake significantly increased fasting arterial pH by 0.04 (95% confidence interval; 0.01-0.08; p<0.001) and post-exercise pH by 0.07 (95% confidence interval, 0.01-0.10, p=0.03) In the HRW study, fasting bicarbonate was significantly higher after the dosing regimen than before the dosing (30.5 ± 1.9 mEq/L vs. 28.3 ± 2.3 mEq/L; p<0.0001). No volunteers withdrew before the end of the study, and no participants reported any annoying side effects from the supplement. These results support the hypothesis that HRW administration is safe and may have an alkalizing effect in young physically active men.


Drinking hydrogen-rich water for 6 weeks reduces reactive oxygen metabolites in the blood and maintains the oxidative potential of the blood. Compared with patients who received placebo water, patients who received hydrogen-rich water had significantly improved quality of life scores during radiotherapy. There was no difference in tumor response to radiation between the two groups.


Daily consumption of hydrogen-rich water is a potential novel therapeutic strategy to improve quality of life after radiation exposure. Drinking hydrogen-rich water reduces the biological response to radiation-induced oxidative stress without affecting the antitumor effect.


reactive oxygen species
quality of life


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