{"id":26820,"date":"2024-01-03T21:38:51","date_gmt":"2024-01-03T19:38:51","guid":{"rendered":"https:\/\/hho-bulgaria.com\/h2-mitigates-osteoarthritis-via-jnk-pathway\/"},"modified":"2024-01-29T21:25:20","modified_gmt":"2024-01-29T19:25:20","slug":"h2-mitigates-osteoarthritis-via-jnk-pathway","status":"publish","type":"post","link":"https:\/\/hho-bulgaria.com\/en\/h2-mitigates-osteoarthritis-via-jnk-pathway\/","title":{"rendered":"H2 Mitigates Osteoarthritis via JNK Pathway"},"content":{"rendered":"
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J Inflamm Res.<\/a><\/span> 2021; 14: 1387\u20131402. <\/div>\n
Published online 2021 Apr 13. <\/span> doi: <\/span>10.2147\/JIR.S297622<\/a><\/span><\/div>\n<\/div>\n<\/div>\n
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PMCID: <\/span>PMC8053515<\/span><\/div>\n
PMID: 33880054<\/a><\/div>\n<\/div>\n<\/div>\n

Hydrogen (H2<\/sub>) Alleviates Osteoarthritis by Inhibiting Apoptosis and Inflammation via the JNK Signaling Pathway<\/h1>\n
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Hongwei Lu<\/a>,#<\/sup>1,<\/sup>2,<\/sup>3,<\/sup>*<\/sup> Wei Wang<\/a>,#<\/sup>1,<\/sup>2,<\/sup>3,<\/sup>*<\/sup> Xiaodiao Kang<\/a>,#<\/sup>1,<\/sup>2,<\/sup>3,<\/sup>*<\/sup> Zeng Lin<\/a>,1,<\/sup>2,<\/sup>3<\/sup> Jun Pan<\/a>,1,<\/sup>2,<\/sup>3<\/sup> Shaowen Cheng<\/a>,4<\/sup><\/sup> and Jingdong Zhang<\/a>1,<\/sup>2,<\/sup>3<\/sup><\/sup><\/div>\n
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Hongwei Lu<\/h3>\n

1<\/sup>Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, People\u2019s Republic of China<\/p>\n

2<\/sup>The Second School of Medicine, Wenzhou Medical University, Wenzhou, People\u2019s Republic of China<\/p>\n

3<\/sup>Bone Research Institute, The Key Orthopaedic Laboratory of Zhejiang Province, Wenzhou, People\u2019s Republic of China<\/p>\n

Find articles by Hongwei Lu<\/a><\/div>\n<\/div>\n
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Wei Wang<\/h3>\n

1<\/sup>Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, People\u2019s Republic of China<\/p>\n

2<\/sup>The Second School of Medicine, Wenzhou Medical University, Wenzhou, People\u2019s Republic of China<\/p>\n

3<\/sup>Bone Research Institute, The Key Orthopaedic Laboratory of Zhejiang Province, Wenzhou, People\u2019s Republic of China<\/p>\n

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Xiaodiao Kang<\/h3>\n

1<\/sup>Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, People\u2019s Republic of China<\/p>\n

2<\/sup>The Second School of Medicine, Wenzhou Medical University, Wenzhou, People\u2019s Republic of China<\/p>\n

3<\/sup>Bone Research Institute, The Key Orthopaedic Laboratory of Zhejiang Province, Wenzhou, People\u2019s Republic of China<\/p>\n

Find articles by Xiaodiao Kang<\/a><\/div>\n<\/div>\n
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Zeng Lin<\/h3>\n

1<\/sup>Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, People\u2019s Republic of China<\/p>\n

2<\/sup>The Second School of Medicine, Wenzhou Medical University, Wenzhou, People\u2019s Republic of China<\/p>\n

3<\/sup>Bone Research Institute, The Key Orthopaedic Laboratory of Zhejiang Province, Wenzhou, People\u2019s Republic of China<\/p>\n

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Jun Pan<\/h3>\n

1<\/sup>Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, People\u2019s Republic of China<\/p>\n

2<\/sup>The Second School of Medicine, Wenzhou Medical University, Wenzhou, People\u2019s Republic of China<\/p>\n

3<\/sup>Bone Research Institute, The Key Orthopaedic Laboratory of Zhejiang Province, Wenzhou, People\u2019s Republic of China<\/p>\n

Find articles by Jun Pan<\/a><\/div>\n<\/div>\n
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Shaowen Cheng<\/h3>\n

4<\/sup>Trauma Center, First Affiliated Hospital of Hainan Medical University, Haikou, People\u2019s Republic of China<\/p>\n

Find articles by Shaowen Cheng<\/a><\/div>\n<\/div>\n
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Jingdong Zhang<\/h3>\n

1<\/sup>Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, People\u2019s Republic of China<\/p>\n

2<\/sup>The Second School of Medicine, Wenzhou Medical University, Wenzhou, People\u2019s Republic of China<\/p>\n

3<\/sup>Bone Research Institute, The Key Orthopaedic Laboratory of Zhejiang Province, Wenzhou, People\u2019s Republic of China<\/p>\n

Find articles by Jingdong Zhang<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Author information<\/a> Article notes<\/a> Copyright and License information<\/a> PMC Disclaimer<\/a><\/div>\n
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1<\/sup>Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, People\u2019s Republic of China<\/div>\n
2<\/sup>The Second School of Medicine, Wenzhou Medical University, Wenzhou, People\u2019s Republic of China<\/div>\n
3<\/sup>Bone Research Institute, The Key Orthopaedic Laboratory of Zhejiang Province, Wenzhou, People\u2019s Republic of China<\/div>\n
4<\/sup>Trauma Center, First Affiliated Hospital of Hainan Medical University, Haikou, People\u2019s Republic of China<\/div>\n
#<\/sup>Contributed equally.<\/div>\n
Correspondence: Shaowen Cheng Trauma Center, First Affiliated Hospital of Hainan Medical University, 31 Long Hua Road, Haikou, 571100, People\u2019s Republic of China, Email chengshaowwn1@126.com<\/div>\n
Jingdong Zhang Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University, 109 Xue Yuan Xi Road, Wenzhou, Zhejiang, 325000, People\u2019s Republic of China, Phone: Tel +86-13587694869, Email zjd4869@163.com<\/div>\n
*<\/sup>These authors contributed equally to this work<\/div>\n<\/div>\n
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Received 2020 Dec 22; Accepted 2021 Mar 18.<\/div>\n<\/div>\n
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Copyright<\/a> \u00a9 2021 Lu et al.<\/div>\n
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