Impact of H2-Enriched Water on Lipid Profile in RatsScientific Research

original title: Effect of Alkaline Water on the Lipid Profile in Wistar Rats


Z Salemi, H Farahani, B Moradi, R Moghadasi

DOI: 10.18869/acadpub.aums.4.3.184



Backgrounds: Alkaline water could be prepared through both electro-chemical and natural ways and previous studies have shown that alkaline water scavenges oxygen radicals in cell culture. It’s expected that alkaline water has positive and preventive effects on diseases related to stress oxidative like atherosclerosis and cardiovascular disease. In recent study, we showed the effects of alkaline water on serum lipid profile in wistar rats. Materials and

Methods: In this study 32 male wistar rats weighing 250-200 g were used. Rats divided randomly into four groups, namely control group, alkaline group 1, alkaline group 2 by adding sodium bicarbonate, and acidic group by adding acetic acid to their drinking water. After 32 weeks, blood samples were obtained and lipid profile was measured in all groups, the data was analyzed with SPSS statistical software.

Results: Relay on obtained results, cholesterol and triglyceride concentrations in alkaline water group1 and 2 to control group and LDL concentrations in alkaline water group1 have been reduced significantly (p<0.5). While LDL concentration in alkaline water group2 and HDL concentrations in alkaline water group1 and 2 to control group have not significant changes.

Conclusion: Results of this study declare that daily administration of alkaline water can improve serum lipid profile and maybe reduced risk of oxidative stress diseases.